Boost Access to Naloxone or Nalmefene

December 2025

New Rx nalmefene auto-injector (Zurnai) will join the plethora of options to reverse opioid overdose.

Use the table below to help keep options straight.

Share the facts. Nalmefene’s duration is 6 hrs versus 2 hrs with naloxone. But there’s no good evidence that nalmefene is more effective.

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